India's agricultural sector ensures food and livelihood security for millions of rural households. However, the adverse effects of climate change pose a severe threat to agricultural sustainability. Compared to conventional practices, sustainable farming offers significant environmental benefits and helps to mitigate climate change impacts. In this article, we examined the effects of integrated nutrient management, organic amendment, no-tillage, crop rotation, residue retention, intercropping, and biochar on C sequestration and the influencing factors and associated economic benefits. A total of 2362 pair-wise observations from 295 studies were included in the meta-analysis framework. The result shows that biochar was the most effective practice for enhancing C sequestration (+41.28 %). Maize-wheat and legume-based cropping systems, medium fine-textured soils, humid-subtropical climate, rainfall, irrigation, and time period were the significant factors that affect carbon sequestration. In addition, our study demonstrated that C sequestration is a dynamic process, and only a limited amount of sequestration is possible from a piece of land. Further, we found that all the improved farming practices that enhance C sequestration were technically feasible and economically profitable. Thus, soil C sequestration through improved crop management practices represents a win-win strategy to combat climate change and conserve natural resources. Therefore, efforts should be directed towards outscaling of sustainable agricultural practices to enhance resilience and adaptation to climate change.